VIP peptide for gut health and IBS — an underrated option
Vasoactive Intestinal Peptide VIP doesn't get enough attention in the peptide community. Most people jump straight to BPC157 for gut issues, but VIP works through completely different mechanisms. VIP is naturally produc…
Vasoactive Intestinal Peptide (VIP) doesn't get enough attention in the peptide community. Most people jump straight to BPC-157 for gut issues, but VIP works through completely different mechanisms.
VIP is naturally produced in your gut and nervous system. It:
- Regulates intestinal motility
- Reduces inflammation in the gut lining
- Modulates the gut-brain axis
- Supports healthy gut barrier function
I've been using it with clients who have IBS, SIBO, and chronic gut inflammation — often after BPC-157 alone wasn't enough.
Protocol I recommend:
- 50mcg subQ daily, building up to 100mcg over 2 weeks
- Run for 4-6 weeks
- Can be stacked with BPC-157 for a comprehensive gut protocol
The research on VIP is extensive but it's mostly in academic journals so it flies under the radar of the biohacking community. Happy to discuss if anyone has questions.
2 Replies
This is exactly what I need. I've done 2 rounds of BPC-157 for gut issues and while it helped with my gastritis, the IBS symptoms (bloating, irregular motility) are still there. Going to try adding VIP. Can you take both simultaneously?
Great write-up Nina. VIP is criminally underused. I've had several clients with mold illness-related gut issues who responded much better to VIP than BPC alone. The gut-brain axis modulation is particularly interesting for people with anxiety-driven IBS.