NAD+ timing around exercise — before or after training?
Training for an Ironman and just added NAD+ to my protocol. Quick question for the community: Do you inject NAD+ before or after training? I've read conflicting opinions: Before: Some say preexercise NAD+ gives you more…
Training for an Ironman and just added NAD+ to my protocol. Quick question for the community:
Do you inject NAD+ before or after training? I've read conflicting opinions:
Before: Some say pre-exercise NAD+ gives you more energy and endurance during the session
After: Others say post-exercise is better because NAD+ supports recovery and you don't want to interfere with the natural stress response of training
I've also seen people say it doesn't matter and the effects are systemic/cumulative rather than acute.
Currently doing 200mg subQ in the morning (I train in the afternoon). Should I switch to post-training? Or morning is fine?
Also — anyone stacking NAD+ with MOTS-C for endurance sports specifically?
5 Replies
For endurance athletes, morning dosing is fine. The effects of NAD+ are cumulative — it's supporting mitochondrial function over weeks, not giving you an acute energy boost. Don't overthink the timing. Consistency > timing.
And yes, NAD+ + MOTS-C is excellent for endurance. They're complementary, not redundant.
I recommend morning dosing for simplicity. The research on timing is sparse but what exists suggests it doesn't significantly matter for subQ administration. For IV NAD+ (which I don't recommend for home use), timing matters more. Stick with your morning routine.
Fellow endurance athlete here (freediving). I do NAD+ morning, MOTS-C morning, and they work great together. My VO2 max has improved and recovery between sessions is noticeably faster. For Ironman training volume, this combo should help significantly.
One thing to consider: some people get a mild flush/warmth from NAD+ which can be distracting during training. If that happens to you, post-training is better. But most people don't notice it after the first week.
Hey Alex,
Great question! Our understanding aligns with what Dan and Nina mentioned — the effects of NAD+ are more about long-term mitochondrial support than immediate energy boosts. So your morning routine seems perfectly fine, especially if it fits well with your schedule. Stick with what feels right for you, as consistency is key.
As for stacking NAD+ with MOTS-C, it's a solid combo for endurance athletes. MOTS-C helps enhance insulin sensitivity and fat metabolism, which can complement the mitochondrial support you're getting from NAD+. Together, they should provide a nice boost to your Ironman training, both in endurance and recovery.
If you haven't experienced any distraction from flushing or warmth with your NAD+ doses, you might not need to adjust. But if you notice it during your sessions, post-training could be a better fit for you. Keep up the great work on your training journey!