NAD+ 500mg
Essential coenzyme studied in research on mitochondrial function, sirtuin signalling, and cellular energy metabolism.
In Stock
SKU: ML-NAD-500MG
💰 Volume Discounts:
Buy 3+ vials = 10% off · Buy 5+ vials = 15% off
NAD+ (Nicotinamide Adenine Dinucleotide) is a ubiquitous coenzyme essential to hundreds of enzymatic reactions in every living cell. Research has established its role as the primary electron acceptor in the mitochondrial electron transport chain, as a substrate for sirtuin enzymes, and as a cofactor for PARP enzymes involved in DNA repair. NAD+ levels are documented to decline with age. Injectable NAD+ is used in research contexts to bypass the limited bioavailability of oral precursors (NMN, NR). For in-vitro and laboratory research use only.
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Community
See all →My longevity stack — feedback? NAD+ / Epithalon / SS-31 / MOTS-C
I've been building what I call my "longevity stack" and want to get feedback from more experienced users: **Current stack:** - NAD+ 200mg subQ EOD (mitochondrial support) - Epithalon 1mg/day x 10 days, every 6 months (telomere maintenance) - SS-31 5mg subQ daily (mitochondrial membrane) - MOTS-C 5mg/week (metabolic/AMPK activation) **Questions:** 1. Is running all four simultaneously overkill? Or do they target different enough pathways? 2. Any negative interactions I should be aware of? 3. Should I cycle any of these or can they be run continuously? 4. Am I missing anything obvious for a longevity-focused protocol? 5. Budget-wise, which ones give the most bang for the buck if I had to drop one? I'm 35, good health, no specific issues — purely interested in optimizing healthspan. Would love input from the practitioners in this community.
SS-31 (Elamipretide) — the mitochondrial peptide nobody talks about
I've been deep-diving into mitochondrial peptides and SS-31 is genuinely fascinating. It targets cardiolipin in the inner mitochondrial membrane and helps restore electron transport chain efficiency. In plain English: it helps your mitochondria produce energy more efficiently, especially in cells that are aging or under stress. The research shows benefits for: - Heart function (originally developed for heart failure) - Exercise capacity in older adults - Kidney function - Possibly neurodegeneration I've been running 5mg subQ daily for 3 weeks. Subjectively I notice: - More sustained energy without the ups and downs - Better exercise recovery (I do hot yoga daily) - Less brain fog in the afternoons It stacks well with NAD+ and MOTS-C for a comprehensive mitochondrial protocol. Curious if anyone else is using it?
NAD+ has been a game changer for my energy levels
I've been doing NAD+ injections for about 6 weeks now. I'm 38 and was dealing with that 3pm energy crash every day — no amount of coffee or sleep seemed to help. Started with 100mg subQ every other day. The first few days I felt a bit flushed and tingly (apparently normal), but by the end of week 1 I noticed I wasn't crashing in the afternoon anymore. Now at week 6, the difference is significant: - Consistent energy throughout the day - Better mental clarity, especially in the mornings - My workouts feel easier (I do hot yoga and strength training) - Sleeping more deeply I know correlation isn't causation but the timing is too perfect. This is the only thing I changed. Would definitely recommend trying it if you're dealing with fatigue.