NAD(+) controls circadian rhythmicity during cardiac aging.

Reveals NAD+ levels regulate circadian clock function in the aging heart.

NAD+ as a central metabolic hub Regulating the hallmarks of aging: Mechanisms and therapeutic implications.

Comprehensive review of NAD+ as a key metabolic regulator of aging hallmarks.

Nicotinamide Mononucleotide Decreases Secretion of Proinflammatory Cytokines via the NAD(+)/SIRT1/p65 Axis.

Demonstrates NMN supplementation reduces inflammatory cytokine secretion through the NAD+/SIRT1/NF-kB pathway.

Changes in the brain [NAD(+)]/[NADH] and [NADPH]/[NADP(+)] with aging and anti-aging dietary restriction.

Characterizes how brain NAD+/NADH ratios change during aging and how dietary restriction can restore them.

Restoring NAD+-Sirtuins Signaling: A Novel Approach to Combat Male Reproductive Aging.

Explores NAD+ and sirtuin pathway restoration as a strategy to counteract age-related reproductive decline.

Intravenous infusion of nicotinamide adenine dinucleotide (NAD(+)) versus nicotinamide riboside (NR): a retrospective tolerability pilot study.

Real-world clinical comparison of IV NAD+ infusion versus oral NR supplementation, evaluating tolerability.

Reduced Versus Oxidized NAD(+) Precursors Drive Distinct Transcriptomic, Proteomic, and Metabolic Profiles in Hepatocytes.

Compares molecular effects of different NAD+ precursors on liver cells.

Panax ginseng Meyer supplementation and potential associations with telomere length and NAD+/NADH ratio in middle-aged adults.

Exploratory human study examining NAD+/NADH ratios and telomere length.