SS-31 50mg
Mitochondria-targeted tetrapeptide that directly protects the inner mitochondrial membrane — restoring cellular energy at its source.
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SKU: ML-SS31-50MG
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SS-31 (Elamipretide) is a mitochondria-targeted tetrapeptide developed by Dr. Hazel Szeto at Weill Cornell Medicine. It selectively concentrates 5,000× in the inner mitochondrial membrane where it binds to cardiolipin — the lipid essential for electron transport chain function and ATP production. As mitochondrial function declines with age and disease, SS-31 acts as a molecular repair agent, directly restoring the energy-generating capacity of cells. It has completed Phase II human clinical trials for heart failure, mitochondrial myopathy, and kidney disease.
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Community
See all →My longevity stack — feedback? NAD+ / Epithalon / SS-31 / MOTS-C
I've been building what I call my "longevity stack" and want to get feedback from more experienced users: **Current stack:** - NAD+ 200mg subQ EOD (mitochondrial support) - Epithalon 1mg/day x 10 days, every 6 months (telomere maintenance) - SS-31 5mg subQ daily (mitochondrial membrane) - MOTS-C 5mg/week (metabolic/AMPK activation) **Questions:** 1. Is running all four simultaneously overkill? Or do they target different enough pathways? 2. Any negative interactions I should be aware of? 3. Should I cycle any of these or can they be run continuously? 4. Am I missing anything obvious for a longevity-focused protocol? 5. Budget-wise, which ones give the most bang for the buck if I had to drop one? I'm 35, good health, no specific issues — purely interested in optimizing healthspan. Would love input from the practitioners in this community.
SS-31 (Elamipretide) — the mitochondrial peptide nobody talks about
I've been deep-diving into mitochondrial peptides and SS-31 is genuinely fascinating. It targets cardiolipin in the inner mitochondrial membrane and helps restore electron transport chain efficiency. In plain English: it helps your mitochondria produce energy more efficiently, especially in cells that are aging or under stress. The research shows benefits for: - Heart function (originally developed for heart failure) - Exercise capacity in older adults - Kidney function - Possibly neurodegeneration I've been running 5mg subQ daily for 3 weeks. Subjectively I notice: - More sustained energy without the ups and downs - Better exercise recovery (I do hot yoga daily) - Less brain fog in the afternoons It stacks well with NAD+ and MOTS-C for a comprehensive mitochondrial protocol. Curious if anyone else is using it?