Mechanisms of Anti-Oxidants, N-Acetylcysteine and Elamipretide (SS-31), on Ozone-Induced Airway Hyperresponsiveness.

Investigates SS-31's antioxidant mechanisms in protecting against ozone-induced airway inflammation.

Endothelial Glycocalyx Degradation as a Mediator of Neuroinflammation and Cognitive Impairment in Aged Rats: Protective Role of SS-31.

Shows SS-31 protects against age-related cognitive decline by preserving the endothelial glycocalyx.

SS-31 improves post-cardiac arrest brain injury by inhibiting microglial ferroptosis and polarization.

Demonstrates SS-31 reduces brain injury after cardiac arrest by preventing ferroptosis in microglia.

Elamipretide in the Management of Barth Syndrome: Current Evidence and a Case Report.

Reviews clinical evidence for elamipretide in treating Barth syndrome, a mitochondrial cardiomyopathy.

Mitochondrial Dysfunction Drives Age-Related Degeneration of the Thoracic Aorta.

Examines how mitochondrial dysfunction drives aortic aging and how SS-31 may protect against it.

Acute mitochondrial reactive oxygen species emissions drive mitochondrial dysfunction after traumatic muscle injury.

Demonstrates SS-31 can mitigate mitochondrial ROS and dysfunction following traumatic muscle injury.

Therapeutic Approaches Involving Mitochondria in the Treatment of Acute Kidney Injury.

Reviews mitochondria-targeted therapies including SS-31 for treating acute kidney injury.

Mitochondrial-Targeted Protective Potential of Elamipretide for the In Vitro Production of Porcine Embryos.

Evaluates SS-31 as a mitochondria-targeted protective agent for improving embryo development.